Mauricio Esguerra is a Senior Project Manager at Nostrum Biodiscovery. He got his B. Sc. in chemistry from Universidad Nacional de Colombia and worked for a while as patent engineer and teacher in physics 101 recitations and labs at the Universidad de los Andes. He then moved to the U.S. to pursue doctoral research under Wilma K. Olson at Rutgers, the State University of New Jersey, looking at the fundamental structural properties of RNA with a combination of methods such as Flory’s biopolymer statistics, Calladine-Drew mechanics, and bioinformatics. Moved right after to Karolinska Institute (K. I.) and worked under Lennart Nilsson on molecular dynamics simulations of Triple Helical DNA relevant to antigene technology. After K. I. he moved to Uppsala University and did research in various topics related to biopolymers, mainly GPCR simulations in collaboration with Hugo Gutiérrez de Terán and studies of the Ribosome with Johan Åqvist. Following on his interest on GPCR’s and databases he joined the GPCRdb as an assistant professor looking into new data concerning the coupling of G-proteins to GPCR’s.
He has published on a broad variety of topics of biological interest and used a wealth of computational chemistry methods, including FEP calculations using the software Q, webservers for GPCR analysis and modeling, RNA and DNA structure and dynamics, and enzyme simulations using the Empirical Valence Bond (EVB) method.